Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy

Proliferative retinopathies are the leading cause of irreversible blindness in all ages, and there is a critical need to identify novel therapies. We investigated the impact of triciribine (TCBN), a tricyclic nucleoside analog and a weak Akt inhibitor, on retinal neurovascular injury, vascular perme...

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Detalles Bibliográficos
Autores principales: Shan, Shengshuai, Liu, Fang, Ford, Edith, Caldwell, Ruth B., Narayanan, S. Priya, Somanath, Payaningal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208444/
https://www.ncbi.nlm.nih.gov/pubmed/37080089
http://dx.doi.org/10.1016/j.biopha.2023.114714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208444/
https://www.ncbi.nlm.nih.gov/pubmed/37080089
http://dx.doi.org/10.1016/j.biopha.2023.114714

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