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Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy
Proliferative retinopathies are the leading cause of irreversible blindness in all ages, and there is a critical need to identify novel therapies. We investigated the impact of triciribine (TCBN), a tricyclic nucleoside analog and a weak Akt inhibitor, on retinal neurovascular injury, vascular perme...
Autores principales: | Shan, Shengshuai, Liu, Fang, Ford, Edith, Caldwell, Ruth B., Narayanan, S. Priya, Somanath, Payaningal R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208444/ https://www.ncbi.nlm.nih.gov/pubmed/37080089 http://dx.doi.org/10.1016/j.biopha.2023.114714 |
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