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Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) consists of fibrotic alveolar remodeling and progressive loss of pulmonary function. Genetic and experimental evidence indicates that chronic alveolar injury and failure to properly repair the respiratory epithelium are intrinsic to IPF pathogenesis. Loss of alveo...

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Detalles Bibliográficos
Autores principales: Warren, Rachel, Lyu, Handeng, Klinkhammer, Kylie, De Langhe, Stijn P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208641/
https://www.ncbi.nlm.nih.gov/pubmed/37166104
http://dx.doi.org/10.7554/eLife.85092