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A Question of Frame: The Role of the Bone Marrow Stromal Niche in Myeloid Malignancies

Until a few years ago, the onset of acute myeloid leukemia (AML) was entirely ascribed to genetic lesions in hematopoietic stem cells. These mutations generate leukemic stem cells, which are known to be the main ones responsible for chemoresistance and relapse. However, in the last years, increasing...

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Detalles Bibliográficos
Autores principales: Tomasoni, Chiara, Pievani, Alice, Rambaldi, Benedetta, Biondi, Andrea, Serafini, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208717/
https://www.ncbi.nlm.nih.gov/pubmed/37234820
http://dx.doi.org/10.1097/HS9.0000000000000896