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M2 macrophage polarization in systemic sclerosis fibrosis: pathogenic mechanisms and therapeutic effects
Systemic sclerosis (SSc, scleroderma), is an autoimmune rheumatic disease characterized by fibrosis of the skin and internal organs, and vasculopathy. Preventing fibrosis by targeting aberrant immune cells that drive extracellular matrix (ECM) over-deposition is a promising therapeutic strategy for...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208842/ https://www.ncbi.nlm.nih.gov/pubmed/37234611 http://dx.doi.org/10.1016/j.heliyon.2023.e16206 |