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Mapping N- to C-terminal allosteric coupling through disruption of a putative CD74 activation site in D-dopachrome tautomerase

The macrophage migration inhibitory factor (MIF) protein family consists of MIF and D-dopachrome tautomerase (also known as MIF-2). These homologs share 34% sequence identity while maintaining nearly indistinguishable tertiary and quaternary structure, which is likely a major contributor to their ov...

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Detalles Bibliográficos
Autores principales: Chen, Emily, Widjaja, Vinnie, Kyro, Gregory, Allen, Brandon, Das, Pragnya, Prahaladan, Varsha M., Bhandari, Vineet, Lolis, Elias J., Batista, Victor S., Lisi, George P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208890/
https://www.ncbi.nlm.nih.gov/pubmed/37080391
http://dx.doi.org/10.1016/j.jbc.2023.104729