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The Sec1–Munc18 protein VPS33B forms a uniquely bidirectional complex with VPS16B

Loss-of-function variants of vacuolar protein sorting proteins VPS33B and VPS16B (VIPAS39) are causative for arthrogryposis, renal dysfunction, and cholestasis syndrome, where early lethality of patients indicates that VPS33B and VPS16B play essential cellular roles. VPS33B is a member of the Sec1–M...

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Detalles Bibliográficos
Autores principales: Liu, Richard J.Y., Al-Molieh, Yusef, Chen, Shao Z., Drobac, Marko, Urban, Denisa, Chen, Chang H., Yao, Helen H.Y., Geng, Ryan S.Q., Li, Ling, Pluthero, Fred G., Benlekbir, Samir, Rubinstein, John L., Kahr, Walter H.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208892/
https://www.ncbi.nlm.nih.gov/pubmed/37062417
http://dx.doi.org/10.1016/j.jbc.2023.104718