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Combining cell-free RNA with cell-free DNA in liquid biopsy for hematologic and solid tumors

Current use of liquid biopsy is based on cell-free DNA (cfDNA) and the evaluation of mutations or methylation pattern. However, expressed RNA can capture mutations, changes in expression levels due to methylation, and provide information on cell of origin, growth, and proliferation status. We develo...

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Detalles Bibliográficos
Autores principales: Albitar, Maher, Zhang, Hong, Charifa, Ahmad, Ip, Andrew, Ma, Wanlong, McCloskey, James, Donato, Michele, Siegel, David, Waintraub, Stanley, Gutierrez, Martin, Pecora, Andrew, Goy, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208940/
https://www.ncbi.nlm.nih.gov/pubmed/37251903
http://dx.doi.org/10.1016/j.heliyon.2023.e16261