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Combining cell-free RNA with cell-free DNA in liquid biopsy for hematologic and solid tumors
Current use of liquid biopsy is based on cell-free DNA (cfDNA) and the evaluation of mutations or methylation pattern. However, expressed RNA can capture mutations, changes in expression levels due to methylation, and provide information on cell of origin, growth, and proliferation status. We develo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208940/ https://www.ncbi.nlm.nih.gov/pubmed/37251903 http://dx.doi.org/10.1016/j.heliyon.2023.e16261 |