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TCF7L2 acts as a molecular switch in midbrain to control mammal vocalization through its DNA binding domain but not transcription activation domain
Vocalization is an essential medium for social signaling in birds and mammals. Periaqueductal gray (PAG) a conserved midbrain structure is believed to be responsible for innate vocalizations, but its molecular regulation remains largely unknown. Here, through a mouse forward genetic screening we ide...
Autores principales: | Qi, Huihui, Luo, Li, Lu, Caijing, Chen, Runze, Zhou, Xianyao, Zhang, Xiaohui, Jia, Yichang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208975/ https://www.ncbi.nlm.nih.gov/pubmed/36782064 http://dx.doi.org/10.1038/s41380-023-01993-5 |
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