Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid

Loss-of-function mutations in patatin-like phospholipase domain-containing protein 1 (PNPLA1) cause autosomal recessive congenital ichthyosis, and altered PNPLA1 activity is implicated in the pathogenesis of atopic dermatitis and other common skin diseases. To examine the hypothesis that PNPLA1 cata...

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Detalles Bibliográficos
Autores principales: Meyer, Jason M., Boeglin, William E., Brash, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209018/
https://www.ncbi.nlm.nih.gov/pubmed/37087101
http://dx.doi.org/10.1016/j.jlr.2023.100379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209018/
https://www.ncbi.nlm.nih.gov/pubmed/37087101
http://dx.doi.org/10.1016/j.jlr.2023.100379

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