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Glycolytically impaired Drosophila glial cells fuel neural metabolism via β-oxidation

Neuronal function is highly energy demanding and thus requires efficient and constant metabolite delivery by glia. Drosophila glia are highly glycolytic and provide lactate to fuel neuronal metabolism. Flies are able to survive for several weeks in the absence of glial glycolysis. Here, we study how...

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Detalles Bibliográficos
Autores principales: McMullen, Ellen, Hertenstein, Helen, Strassburger, Katrin, Deharde, Leon, Brankatschk, Marko, Schirmeier, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209077/
https://www.ncbi.nlm.nih.gov/pubmed/37225684
http://dx.doi.org/10.1038/s41467-023-38813-x