Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene–environment interaction

Gene–environment interactions are believed to play a role in multifactorial phenotypes, although poorly described mechanistically. Cleft lip/palate (CLP), the most common craniofacial malformation, has been associated with both genetic and environmental factors, with little gene–environment interact...

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Detalles Bibliográficos
Autores principales: Alvizi, Lucas, Nani, Diogo, Brito, Luciano Abreu, Kobayashi, Gerson Shigeru, Passos-Bueno, Maria Rita, Mayor, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209087/
https://www.ncbi.nlm.nih.gov/pubmed/37225711
http://dx.doi.org/10.1038/s41467-023-38526-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209087/
https://www.ncbi.nlm.nih.gov/pubmed/37225711
http://dx.doi.org/10.1038/s41467-023-38526-1

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