16p11.2 deletion mice exhibit compromised fronto-temporal connectivity, GABAergic dysfunction, and enhanced attentional ability

Autism spectrum disorders are more common in males, and have a substantial genetic component. Chromosomal 16p11.2 deletions in particular carry strong genetic risk for autism, yet their neurobiological impact is poorly characterised, particularly at the integrated systems level. Here we show that mi...

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Detalles Bibliográficos
Autores principales: Openshaw, Rebecca L., Thomson, David M., Bristow, Greg C., Mitchell, Emma J., Pratt, Judith A., Morris, Brian J., Dawson, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209099/
https://www.ncbi.nlm.nih.gov/pubmed/37225770
http://dx.doi.org/10.1038/s42003-023-04891-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209099/
https://www.ncbi.nlm.nih.gov/pubmed/37225770
http://dx.doi.org/10.1038/s42003-023-04891-2

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