A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells

Internalization of complement membrane attack complexes (MACs) assembles NLRP3 inflammasomes in endothelial cells (EC) and promotes IL-β-mediated tissue inflammation. Informed by proteomics analyses of FACS-sorted inflammasomes, we identify a protein complex modulating inflammasome activity on endos...

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Detalles Bibliográficos
Autores principales: Li, Xue, Jiang, Quan, Song, Guiyu, Barkestani, Mahsa Nouri, Wang, Qianxun, Wang, Shaoxun, Fan, Matthew, Fang, Caodi, Jiang, Bo, Johnson, Justin, Geirsson, Arnar, Tellides, George, Pober, Jordan S., Jane-wit, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209169/
https://www.ncbi.nlm.nih.gov/pubmed/37225719
http://dx.doi.org/10.1038/s41467-023-38684-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209169/
https://www.ncbi.nlm.nih.gov/pubmed/37225719
http://dx.doi.org/10.1038/s41467-023-38684-2

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