Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells

Single-cell approaches have revealed that the haematopoietic hierarchy is a continuum of differentiation, from stem cell to committed progenitor, marked by changes in gene expression. However, many of these approaches neglect isoform-level information and thus do not capture the extent of alternativ...

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Detalles Bibliográficos
Autores principales: Mincarelli, Laura, Uzun, Vladimir, Wright, David, Scoones, Anita, Rushworth, Stuart A., Haerty, Wilfried, Macaulay, Iain C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209181/
https://www.ncbi.nlm.nih.gov/pubmed/37225862
http://dx.doi.org/10.1038/s42003-023-04936-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209181/
https://www.ncbi.nlm.nih.gov/pubmed/37225862
http://dx.doi.org/10.1038/s42003-023-04936-6

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