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Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells
Single-cell approaches have revealed that the haematopoietic hierarchy is a continuum of differentiation, from stem cell to committed progenitor, marked by changes in gene expression. However, many of these approaches neglect isoform-level information and thus do not capture the extent of alternativ...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209181/ https://www.ncbi.nlm.nih.gov/pubmed/37225862 http://dx.doi.org/10.1038/s42003-023-04936-6 |