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Overloaded axial stress activates the Wnt/β-Catenin pathway in nucleus pulposus cells of adult degenerative scoliosis combined with intervertebral disc degeneration

BACKGROUND: Intervertebral disc degeneration (IVDD) is the initiating factor of adult degenerative scoliosis (ADS), and ADS further accelerates IVDD, creating a vicious cycle. Nevertheless, the role of the Wnt/β-Catenin pathway in ADS combined with IVDD (ADS-IVDD) remains a mystery. Accordingly, thi...

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Detalles Bibliográficos
Autores principales: Cai, Zhijun, Luo, Qibiao, Yang, Xi, Pu, Luqiao, Zong, Haiyang, Shi, Rongmao, He, Pengju, Xu, Yongqing, Li, Yang, Zhang, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209306/
https://www.ncbi.nlm.nih.gov/pubmed/37031322
http://dx.doi.org/10.1007/s11033-023-08390-9