Cargando…
Overloaded axial stress activates the Wnt/β-Catenin pathway in nucleus pulposus cells of adult degenerative scoliosis combined with intervertebral disc degeneration
BACKGROUND: Intervertebral disc degeneration (IVDD) is the initiating factor of adult degenerative scoliosis (ADS), and ADS further accelerates IVDD, creating a vicious cycle. Nevertheless, the role of the Wnt/β-Catenin pathway in ADS combined with IVDD (ADS-IVDD) remains a mystery. Accordingly, thi...
Autores principales: | Cai, Zhijun, Luo, Qibiao, Yang, Xi, Pu, Luqiao, Zong, Haiyang, Shi, Rongmao, He, Pengju, Xu, Yongqing, Li, Yang, Zhang, Jianping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209306/ https://www.ncbi.nlm.nih.gov/pubmed/37031322 http://dx.doi.org/10.1007/s11033-023-08390-9 |
Ejemplares similares
-
Autologous fibroblasts induce fibrosis of the nucleus pulposus to maintain the stability of degenerative intervertebral discs
por: Chen, Chen, et al.
Publicado: (2020) -
Stiffening of the nucleus pulposus upon axial loading of the intervertebral disc: An experimental in situ study
por: Beekmans, Steven V., et al.
Publicado: (2018) -
Static axial overloading primes lumbar caprine intervertebral discs for posterior herniation
por: Paul, Cornelis P. L., et al.
Publicado: (2017) -
Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats
por: Wang, Feng, et al.
Publicado: (2019) -
Dynamic and Static Overloading Induce Early Degenerative Processes in Caprine Lumbar Intervertebral Discs
por: Paul, Cornelis P. L., et al.
Publicado: (2013)