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Novel dicarbonyl metabolic pathway via mitochondrial ES1 possessing glyoxalase III activity
Glycation, caused by reactive dicarbonyls, plays a role in various diseases by forming advanced glycation end products. In live cells, reactive dicarbonyls such as glyoxal (GO) and methylglyoxal (MGO) are produced during cell metabolism, and these should be removed consistently. However, the dicarbo...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209487/ https://www.ncbi.nlm.nih.gov/pubmed/37250100 http://dx.doi.org/10.1016/j.bbadva.2023.100092 |