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Novel dicarbonyl metabolic pathway via mitochondrial ES1 possessing glyoxalase III activity

Glycation, caused by reactive dicarbonyls, plays a role in various diseases by forming advanced glycation end products. In live cells, reactive dicarbonyls such as glyoxal (GO) and methylglyoxal (MGO) are produced during cell metabolism, and these should be removed consistently. However, the dicarbo...

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Detalles Bibliográficos
Autores principales:	Ito, Ginga, Tatara, Yota, Itoh, Ken, Yamada, Miwa, Yamashita, Tetsuro, Sakamoto, Kimitoshi, Nozaki, Takayuki, Ishida, Kinji, Wake, Yui, Kaneko, Takehito, Fukuda, Tomokazu, Sugano, Eriko, Tomita, Hiroshi, Ozaki, Taku
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209487/ https://www.ncbi.nlm.nih.gov/pubmed/37250100 http://dx.doi.org/10.1016/j.bbadva.2023.100092

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