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Loss of chondroitin sulfate proteoglycan sulfation allows delayed sympathetic reinnervation after cardiac ischemia–reperfusion

Sympathetic nerve loss in the heart predicts the risk of ventricular arrhythmias after myocardial infarction (MI) in patients. Sympathetic denervation after cardiac ischemia–reperfusion is sustained by matrix components chondroitin sulfate proteoglycans (CSPGs) in the cardiac scar. We showed that 4,...

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Detalles Bibliográficos
Autores principales: Blake, Matthew R., Parrish, Diana C., Staffenson, Melanie A., Johnson, Morgan A., Woodward, William R., Habecker, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209516/
https://www.ncbi.nlm.nih.gov/pubmed/37226390
http://dx.doi.org/10.14814/phy2.15702