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Reprogramming of iron metabolism confers ferroptosis resistance in ECM-detached cells

Cancer cells often acquire resistance to cell death programs induced by loss of integrin-mediated attachment to extracellular matrix (ECM). Given that adaptation to ECM-detached conditions can facilitate tumor progression and metastasis, there is significant interest in effective elimination of ECM-...

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Detalles Bibliográficos
Autores principales: He, Jianping, Abikoye, Abigail M., McLaughlin, Brett P., Middleton, Ryan S., Sheldon, Ryan, Jones, Russell G., Schafer, Zachary T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
https://www.ncbi.nlm.nih.gov/pubmed/37250802
http://dx.doi.org/10.1016/j.isci.2023.106827