Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation

Seven in absentia homolog 1 (SIAH1) was reported to be downregulated in hepatocellular carcinoma (HCC) and played an important role in HCC progression; however, the underlying reason remains unknown. Here, we found that Cathepsin K (CTSK), a protein potentially interacting with SIAH1, inhibits SIAH1...

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Detalles Bibliográficos
Autores principales: Zhang, Chengming, Liu, Zhiyi, Wang, Xiaotian, Zhang, Bin, Cui, Licheng, Hu, Qinghe, Hu, Bin, Cao, Kuan, Shan, Wengang, Shi, Hengliang, Wang, Renhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209540/
https://www.ncbi.nlm.nih.gov/pubmed/37250786
http://dx.doi.org/10.1016/j.isci.2023.106852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209540/
https://www.ncbi.nlm.nih.gov/pubmed/37250786
http://dx.doi.org/10.1016/j.isci.2023.106852

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