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Contribution of the hexosamine biosynthetic pathway in the hyperglycemia-dependent and -independent breakdown of the retinal neurovascular unit

BACKGROUND: Diabetic retinopathy (DR) remains one of the most common complications of diabetes despite great efforts to uncover its underlying mechanisms. The pathogenesis of DR is characterized by the deterioration of the neurovascular unit (NVU), showing damage of vascular cells, activation of gli...

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Detalles Bibliográficos
Autores principales: Wang, Yixin, Eshwaran, Rachana, Beck, Susanne C., Hammes, Hans-Peter, Wieland, Thomas, Feng, Yuxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209545/
https://www.ncbi.nlm.nih.gov/pubmed/37172821
http://dx.doi.org/10.1016/j.molmet.2023.101736