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Transferrin, insulin, and progesterone modulate intracellular concentrations of coenzyme Q and cholesterol, products of the mevalonate pathway, in undifferentiated PC12 cells

Coenzyme Q (CoQ) is important not only as an essential lipid for the mitochondrial electron transport system, but also as an antioxidant. CoQ levels decrease during aging and in various diseases. Orally administered CoQ is not readily taken up in the brain, so it is necessary to develop a method to...

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Detalles Bibliográficos
Autores principales: Nakamura, Akari, Aida, Yukina, Okamoto, Mizuho, Maeda, Ayaka, Nagao, Ayaka, Kitatani, Kanae, Takekoshi, Susumu, Fujisawa, Akio, Yamamoto, Yorihiro, Kashiba, Misato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209592/
https://www.ncbi.nlm.nih.gov/pubmed/37251957
http://dx.doi.org/10.3164/jcbn.22-115