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Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo

Cell therapy for Parkinson’s disease has experienced substantial growth in the past decades with several ongoing clinical trials. Despite increasing refinement of differentiation protocols and standardization of the transplanted neural precursors, the transcriptomic analysis of cells in the transpla...

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Detalles Bibliográficos
Autores principales: Rájová, Jana, Davidsson, Marcus, Avallone, Martino, Hartnor, Morgan, Aldrin-Kirk, Patrick, Cardoso, Tiago, Nolbrant, Sara, Mollbrink, Annelie, Storm, Petter, Heuer, Andreas, Parmar, Malin, Björklund, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209706/
https://www.ncbi.nlm.nih.gov/pubmed/37251982
http://dx.doi.org/10.1016/j.omtm.2023.04.008