Gene, cell type, and drug prioritization analysis suggest genetic basis for the utility of diuretics in treating Alzheimer disease

We introduce a user-friendly tool for risk gene, cell type, and drug prioritization for complex traits: GCDPipe. It uses gene-level GWAS-derived data and gene expression data to train a model for the identification of disease risk genes and relevant cell types. Gene prioritization information is the...

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Detalles Bibliográficos
Autores principales: Pinakhina, Daria, Loboda, Alexander, Sergushichev, Alexey, Artomov, Mykyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209737/
https://www.ncbi.nlm.nih.gov/pubmed/37250495
http://dx.doi.org/10.1016/j.xhgg.2023.100203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209737/
https://www.ncbi.nlm.nih.gov/pubmed/37250495
http://dx.doi.org/10.1016/j.xhgg.2023.100203

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