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Combined therapy with dapagliflozin and entresto offers an additional benefit on improving the heart function in rat after ischemia-reperfusion injury

BACKGROUND: This study tested whether combined dapagliflozin and entresto treatment would be superior to either one alone for preserving the left-ventricular ejection-fraction (LVEF) in rat after ischemia-reperfusion (IR) injury. METHODS: Cell culture using H9C2 cells and IR injury in rat with dapag...

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Detalles Bibliográficos
Autores principales: Ko, Sheung-Fat, Sung, Pei Hsun, Yang, Chih Chao, Chiang, John Y., Yip, Hon Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209741/
https://www.ncbi.nlm.nih.gov/pubmed/35718305
http://dx.doi.org/10.1016/j.bj.2022.06.002