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Hypochlorite-induced oxidation promotes aggregation and reduces toxicity of amyloid beta 1-42

Exacerbated hypochlorite (OCl(−)) production is linked to neurodegenerative processes, but there is growing evidence that lower levels of hypochlorite activity are important to protein homeostasis. In this study we characterise the effects of hypochlorite on the aggregation and toxicity of amyloid b...

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Detalles Bibliográficos
Autores principales: Mañucat-Tan, Noralyn B., Chowdhury, Ashfaq, Cataldi, Rodrigo, Abdullah, Rafaa Zeineddine, Kumita, Janet R., Wyatt, Amy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209884/
https://www.ncbi.nlm.nih.gov/pubmed/37216700
http://dx.doi.org/10.1016/j.redox.2023.102736