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Hypochlorite-induced oxidation promotes aggregation and reduces toxicity of amyloid beta 1-42
Exacerbated hypochlorite (OCl(−)) production is linked to neurodegenerative processes, but there is growing evidence that lower levels of hypochlorite activity are important to protein homeostasis. In this study we characterise the effects of hypochlorite on the aggregation and toxicity of amyloid b...
Autores principales: | Mañucat-Tan, Noralyn B., Chowdhury, Ashfaq, Cataldi, Rodrigo, Abdullah, Rafaa Zeineddine, Kumita, Janet R., Wyatt, Amy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209884/ https://www.ncbi.nlm.nih.gov/pubmed/37216700 http://dx.doi.org/10.1016/j.redox.2023.102736 |
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