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Ivermectin Protects Against Experimental Autoimmune Encephalomyelitis in Mice by Modulating the Th17/Treg Balance Involved in the IL-2/STAT5 Pathway

Multiple sclerosis (MS), a T-cell-mediated autoimmune disease that affects the central nervous system (CNS), is characterized by white matter demyelination, axon destruction, and oligodendrocyte degeneration. Ivermectin, an anti-parasitic drug, has anti-inflammatory, anti-tumor, and antiviral proper...

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Detalles Bibliográficos
Autores principales: Xie, Yu, Jin, Chaolei, Sang, Hongzhen, Liu, Wenhua, Wang, Junpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209955/
https://www.ncbi.nlm.nih.gov/pubmed/37227550
http://dx.doi.org/10.1007/s10753-023-01829-y