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Inhibition Effect and Molecular Mechanisms of Quercetin on the Aβ42 Dimer: A Molecular Dynamics Simulation Study

[Image: see text] Amyloid-β (Aβ) dimer as the smallest oligomer has recently been drawing attention due to its neurotoxicity, transient nature, and heterogeneity. The inhibition of Aβ dimer’s aggregation is the key to primary intervention of Alzheimer’s disease. Previous experimental studies have re...

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Detalles Bibliográficos
Autores principales: Fang, Mei, Wang, Xin, Su, Kehe, Jia, Xingang, Guan, Ping, Hu, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210038/
https://www.ncbi.nlm.nih.gov/pubmed/37251196
http://dx.doi.org/10.1021/acsomega.3c01208