Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy

BACKGROUND: Renal medullary carcinoma (RMC) is a highly aggressive cancer in need of new therapeutic strategies. The neddylation pathway can protect cells from DNA damage induced by the platinum‐based chemotherapy used in RMC. We investigated if neddylation inhibition with pevonedistat will synergis...

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Detalles Bibliográficos
Autores principales: Shapiro, Daniel D., Zacharias, Niki Millward, Tripathi, Durga N., Karki, Menuka, Bertocchio, Jean‐Philippe, Soeung, Melinda, He, Rong, Westerman, Mary E., Gao, Jianjun, Rao, Priya, Lam, Truong N. A., Jonasch, Eric, Perelli, Luigi, Cheng, Emily H., Carugo, Alessandro, Heffernan, Timothy P., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M., Karam, Jose A., Msaouel, Pavlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210052/
https://www.ncbi.nlm.nih.gov/pubmed/37226898
http://dx.doi.org/10.1002/ctm2.1267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210052/
https://www.ncbi.nlm.nih.gov/pubmed/37226898
http://dx.doi.org/10.1002/ctm2.1267

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