From methodological limitations to the function of metallothioneins - a guide to approaches for determining weak, moderate, and tight affinity zinc sites

Mammalian metallothioneins (MTs) are small cysteine-rich proteins whose primary role is participation in zinc and copper homeostasis. Ever since their discovery, MTs have been investigated in terms of metal-binding affinity. The initial concept of seven Zn(II) ions (Zn(7)MT) bound with the same, und...

Descripción completa

Detalles Bibliográficos
Autores principales: Pomorski, Adam, Drozd, Agnieszka, Kocyła, Anna, Krężel, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210066/
https://www.ncbi.nlm.nih.gov/pubmed/37113075
http://dx.doi.org/10.1093/mtomcs/mfad027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210066/
https://www.ncbi.nlm.nih.gov/pubmed/37113075
http://dx.doi.org/10.1093/mtomcs/mfad027

Ejemplares similares