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Allosteric modulators of solute carrier function: a theoretical framework

Large-scale drug screening is currently the basis for the identification of new chemical entities. This is a rather laborious approach, because a large number of compounds must be tested to cover the chemical space in an unbiased fashion. However, the structures of targetable proteins have become in...

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Detalles Bibliográficos
Autores principales: Boytsov, D., Schicker, K., Hellsberg, E., Freissmuth, M., Sandtner, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210158/
https://www.ncbi.nlm.nih.gov/pubmed/37250134
http://dx.doi.org/10.3389/fphys.2023.1166450