Design and Synthesis of 2-(4-Bromophenyl)Quinoline-4-Carbohydrazide Derivatives via Molecular Hybridization as Novel Microbial DNA-Gyrase Inhibitors

[Image: see text] Microbial DNA gyrase is regarded as an outstanding microbial target. Hence, 15 new quinoline derivatives (5–14) were designed and synthesized. The antimicrobial activity of the afforded compounds was pursued via in vitro approaches. The investigated compounds displayed eligible MIC...

Descripción completa

Detalles Bibliográficos
Autores principales: Abd El-Lateef, Hany M., Elmaaty, Ayman Abo, Abdel Ghany, Lina M. A., Abdel-Aziz, Mohamed S., Zaki, Islam, Ryad, Noha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210181/
https://www.ncbi.nlm.nih.gov/pubmed/37251193
http://dx.doi.org/10.1021/acsomega.3c01156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210181/
https://www.ncbi.nlm.nih.gov/pubmed/37251193
http://dx.doi.org/10.1021/acsomega.3c01156

Ejemplares similares