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Design and Synthesis of 2-(4-Bromophenyl)Quinoline-4-Carbohydrazide Derivatives via Molecular Hybridization as Novel Microbial DNA-Gyrase Inhibitors
[Image: see text] Microbial DNA gyrase is regarded as an outstanding microbial target. Hence, 15 new quinoline derivatives (5–14) were designed and synthesized. The antimicrobial activity of the afforded compounds was pursued via in vitro approaches. The investigated compounds displayed eligible MIC...
Autores principales: | Abd El-Lateef, Hany M., Elmaaty, Ayman Abo, Abdel Ghany, Lina M. A., Abdel-Aziz, Mohamed S., Zaki, Islam, Ryad, Noha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210181/ https://www.ncbi.nlm.nih.gov/pubmed/37251193 http://dx.doi.org/10.1021/acsomega.3c01156 |
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