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Molecular Dynamics Simulations of Ion Permeation in Human Voltage-Gated Sodium Channels

[Image: see text] The recent determination of cryo-EM structures of voltage-gated sodium (Na(v)) channels has revealed many details of these proteins. However, knowledge of ionic permeation through the Na(v) pore remains limited. In this work, we performed atomistic molecular dynamics (MD) simulatio...

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Detalles Bibliográficos
Autores principales: Alberini, Giulio, Alexis Paz, Sergio, Corradi, Beatrice, Abrams, Cameron F., Benfenati, Fabio, Maragliano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210251/
https://www.ncbi.nlm.nih.gov/pubmed/37116214
http://dx.doi.org/10.1021/acs.jctc.2c00990