Analgesia by intrathecal delta-9-tetrahydrocannabinol is dependent on Cav3.2 calcium channels

Delta-9-tetrahydrocannabinol (Δ(9)-THC) is known to produce systemic analgesia that involves CB(1) and CB(2) cannabinoid receptors. However, there is compelling evidence that Δ(9)-THC can potently inhibit Cav3.2T-type calcium channels which are highly expressed in dorsal root ganglion neurons and in...

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Detalles Bibliográficos
Autores principales: Gadotti, Vinicius de Maria, Antunes, Flavia Tasmin Techera, Zamponi, Gerald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210369/
https://www.ncbi.nlm.nih.gov/pubmed/37231418
http://dx.doi.org/10.1186/s13041-023-01036-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210369/
https://www.ncbi.nlm.nih.gov/pubmed/37231418
http://dx.doi.org/10.1186/s13041-023-01036-8

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