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Analgesia by intrathecal delta-9-tetrahydrocannabinol is dependent on Cav3.2 calcium channels
Delta-9-tetrahydrocannabinol (Δ(9)-THC) is known to produce systemic analgesia that involves CB(1) and CB(2) cannabinoid receptors. However, there is compelling evidence that Δ(9)-THC can potently inhibit Cav3.2T-type calcium channels which are highly expressed in dorsal root ganglion neurons and in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210369/ https://www.ncbi.nlm.nih.gov/pubmed/37231418 http://dx.doi.org/10.1186/s13041-023-01036-8 |