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Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice

BACKGROUND: Alzheimer's disease is accompanied by an abnormal high accumulation of cis-P tau. However, the long-term changes in behavior following tau accumulation remains under debate. The present study investigated the long-term effects of tauopathy on learning and memory, synaptic plasticity...

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Detalles Bibliográficos
Autores principales: Fatemeh, Bakhtiarzadeh, Koorosh, Shahpasand, Amir, Shojaei, Yaghoub, Fathollahi, Javad, Mirnajafi-Zadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210374/
https://www.ncbi.nlm.nih.gov/pubmed/37231523
http://dx.doi.org/10.1186/s12993-023-00211-0