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Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model

BACKGROUND: Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular vesicles (MSC-EVs) hold promise as a disease modifying treatment in osteoarthritis (OA). Obesity, and its associated inflammation, contribute to OA development and metabolic OA represents a specific and significant group...

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Detalles Bibliográficos
Autores principales: Warmink, Kelly, Rios, Jaqueline L., Varderidou-Minasian, Suzy, Torres-Torrillas, Marta, van Valkengoed, Devin R., Versteeg, Sabine, Eijkelkamp, Niels, Weinans, Harrie, Korthagen, Nicoline M., Lorenowicz, Magdalena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210425/
https://www.ncbi.nlm.nih.gov/pubmed/37226203
http://dx.doi.org/10.1186/s13287-023-03368-7