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CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis

BACKGROUND: The axonemal microtubules of primary cilium undergo a conserved protein posttranslational modification (PTM) — polyglutamylation. This reversible procedure is processed by tubulin tyrosine ligase-like polyglutamylases to form secondary polyglutamate side chains, which are metabolized by...

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Detalles Bibliográficos
Autores principales: Wang, Yujuan, Zhang, Yuan, Guo, Xinyu, Zheng, Yiqiang, Zhang, Xinjie, Feng, Shanshan, Wu, Hui-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210458/
https://www.ncbi.nlm.nih.gov/pubmed/37226238
http://dx.doi.org/10.1186/s12915-023-01622-1