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CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis
BACKGROUND: The axonemal microtubules of primary cilium undergo a conserved protein posttranslational modification (PTM) — polyglutamylation. This reversible procedure is processed by tubulin tyrosine ligase-like polyglutamylases to form secondary polyglutamate side chains, which are metabolized by...
Autores principales: | Wang, Yujuan, Zhang, Yuan, Guo, Xinyu, Zheng, Yiqiang, Zhang, Xinjie, Feng, Shanshan, Wu, Hui-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210458/ https://www.ncbi.nlm.nih.gov/pubmed/37226238 http://dx.doi.org/10.1186/s12915-023-01622-1 |
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