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Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly – comparative results from the KORA and AugUR study

BACKGROUND: Polygenic scores (PGSs) combining genetic variants found to be associated with creatinine-based estimated glomerular filtration rate (eGFR(crea)) have been applied in various study populations with different age ranges. This has shown that PGS explain less eGFR(crea) variance in the elde...

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Detalles Bibliográficos
Autores principales: Herold, Janina M., Nano, Jana, Gorski, Mathias, Winkler, Thomas W., Stanzick, Kira J., Zimmermann, Martina E., Brandl, Caroline, Peters, Annette, Koenig, Wolfgang, Burkhardt, Ralph, Gessner, André, Heid, Iris M., Gieger, Christian, Stark, Klaus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210501/
https://www.ncbi.nlm.nih.gov/pubmed/37231333
http://dx.doi.org/10.1186/s12863-023-01130-9