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Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly – comparative results from the KORA and AugUR study
BACKGROUND: Polygenic scores (PGSs) combining genetic variants found to be associated with creatinine-based estimated glomerular filtration rate (eGFR(crea)) have been applied in various study populations with different age ranges. This has shown that PGS explain less eGFR(crea) variance in the elde...
Autores principales: | Herold, Janina M., Nano, Jana, Gorski, Mathias, Winkler, Thomas W., Stanzick, Kira J., Zimmermann, Martina E., Brandl, Caroline, Peters, Annette, Koenig, Wolfgang, Burkhardt, Ralph, Gessner, André, Heid, Iris M., Gieger, Christian, Stark, Klaus J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210501/ https://www.ncbi.nlm.nih.gov/pubmed/37231333 http://dx.doi.org/10.1186/s12863-023-01130-9 |
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