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Modeling early germline immunization after horizontal transfer of transposable elements reveals internal piRNA cluster heterogeneity

BACKGROUND: A fraction of all genomes is composed of transposable elements (TEs) whose mobility needs to be carefully controlled. In gonads, TE activity is repressed by PIWI-interacting RNAs (piRNAs), a class of small RNAs synthesized by heterochromatic loci enriched in TE fragments, called piRNA cl...

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Detalles Bibliográficos
Autores principales: Asif-Laidin, Amna, Casier, Karine, Ziriat, Zoheir, Boivin, Antoine, Viodé, Elise, Delmarre, Valérie, Ronsseray, Stéphane, Carré, Clément, Teysset, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210503/
https://www.ncbi.nlm.nih.gov/pubmed/37226160
http://dx.doi.org/10.1186/s12915-023-01616-z