Exogenous All-Trans Retinoic Acid Induces Myopia and Alters Scleral Biomechanics in Mice

PURPOSE: Ocular all-trans retinoic acid (atRA) levels are influenced by visual cues, and exogenous atRA has been shown to increase eye size in chickens and guinea pigs. However, it is not clear whether atRA induces myopic axial elongation via scleral changes. Here, we test the hypothesis that exogen...

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Detalles Bibliográficos
Autores principales: Brown, Dillon M., Yu, Jianshi, Kumar, Praveen, Paulus, Quinn M., Kowalski, Michael A., Patel, Jay M., Kane, Maureen A., Ethier, C. Ross, Pardue, Machelle T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Anatomy and Pathology/Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210516/
https://www.ncbi.nlm.nih.gov/pubmed/37219510
http://dx.doi.org/10.1167/iovs.64.5.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210516/
https://www.ncbi.nlm.nih.gov/pubmed/37219510
http://dx.doi.org/10.1167/iovs.64.5.22

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