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Exogenous All-Trans Retinoic Acid Induces Myopia and Alters Scleral Biomechanics in Mice
PURPOSE: Ocular all-trans retinoic acid (atRA) levels are influenced by visual cues, and exogenous atRA has been shown to increase eye size in chickens and guinea pigs. However, it is not clear whether atRA induces myopic axial elongation via scleral changes. Here, we test the hypothesis that exogen...
Autores principales: | Brown, Dillon M., Yu, Jianshi, Kumar, Praveen, Paulus, Quinn M., Kowalski, Michael A., Patel, Jay M., Kane, Maureen A., Ethier, C. Ross, Pardue, Machelle T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210516/ https://www.ncbi.nlm.nih.gov/pubmed/37219510 http://dx.doi.org/10.1167/iovs.64.5.22 |
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