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MHC Architecture in Amphibians—Ancestral Reconstruction, Gene Rearrangements, and Duplication Patterns

The hypervariable major histocompatibility complex (MHC) is a crucial component of vertebrate adaptive immunity, but large-scale studies on MHC macroevolution in nonmodel vertebrates have long been constrained by methodological limitations. Here, we used rapidly accumulating genomic data to reconstr...

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Detalles Bibliográficos
Autores principales: He, Ke, Babik, Wiesław, Majda, Mateusz, Minias, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210626/
https://www.ncbi.nlm.nih.gov/pubmed/37170911
http://dx.doi.org/10.1093/gbe/evad079